Lungs

The sequestration of myeloid precursors into the pulmonary parenchyma can lead to symptomatic pulmonary hypertension in MMM.10 We have recently reported our experience with single-fraction, low-dose (100 cGy) external beam radiation to the lungs for palliating MMM-associated pulmonary hypertension.94 A total of seven patients at our institution have experienced a palliative benefit from pulmonary XRT demonstrated by improved performance status, decreased pulmonary artery pressures on echocardiography, and less EMH on lung 99mTc sulfur colloid scans.

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