Medical Surgical And Radiotherapeutic Options In Cimf

No therapy, other than perhaps stem cell transplant, has been shown to impact the survival of MMM patients. Thus, nontransplant management strategies are palliative in orientation and goal. When palliative therapy is appropriate, it is necessary to identify which disease manifestations truly affect quality of life (see Figure 49.1). Currently, there has been only modest success with palliating myeloproliferative and cytope-nia-associated symptoms, with no real success in either improving MMM-associated constitutional symptoms or preventing blastic transformation.

Table 49.1

Published results for hematopoietic stem cell transplantation in MMM

Age median Mortality

Reference Disease Graft N (range) Conditioning <Day 100 NRM

0 0

Post a comment