Na

35% at

23% at 5 years

Two-institution trial 5 years

aIncludes low-grade histologies (a total of 35 patients reported but only 20 had aggressive NHL).

Alio SCT, allogeneic stem cell transplantation; int-grade, intermediate-grade non-Hodgkin's lymphoma; PFS, progression-free survival; EFS, event-free survival; OS, overall survival.

aIncludes low-grade histologies (a total of 35 patients reported but only 20 had aggressive NHL).

Alio SCT, allogeneic stem cell transplantation; int-grade, intermediate-grade non-Hodgkin's lymphoma; PFS, progression-free survival; EFS, event-free survival; OS, overall survival.

Besien and coworkers29 noted that diffuse large-cell NHL was among the least sensitive to the GvL effect. In fact, in two series of allo SCT in low-grade NHL by Toze and colleagues26 and Forrest et al.,27 no relapses were reported; additionally, two relapses after allo SCT were reinduced into a complete remission using chemotherapy, indicating that all 16 allografts were alive in complete remission.

Table 65.5 Selected studies using myeloablative conditioning and allo SCT for follicular NHL
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