Nsmm

(1) Monoclonal plasma cells in the bone marrow

<10%

>10%

>10%

(2) M-spike: serum IgG or serum IgA or urine Bence Jones protein

>3.0 g/dl >2.0 g/dl >1.0 g/24 h absent3 absent3 absent3

(2) M-spike: serum IgG or serum IgA or urine Bence Jones protein

>3.0 g/dl >2.0 g/dl >1.0 g/24 h absent3 absent3 absent3

(3) End organ damage absent absent presnet aby immunofixation.

Presence of all three criteria are required for diagnosis, except in SM where only one of (1) and (2) criteria is sufficient.

Table 82.6 Solitary plasmacytoma of the bone, solitary extramedullary plasmacytoma

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