Ovarian Tissue Cryopreservation

Ovarian tissue banking in humans is being considered to restore fertility in patients who lose ovarian function because of chemotherapy or radiotherapy.56 Ovarian tissue cryopreservation and transplantation was first examined in rodent studies and then in sheep and human ovarian xenograft studies.57 However, no pregnancies have been reported in humans from the use of cryopreserved ovarian tissue. Although promising, there is a theoretical risk that malignant stem cells will be reimplanted along with the thawed cryopreserved ovary.58 59 With the publication of promising data from humans, ovarian tissue cryopreservation from selected patients before cancer treatment and in those requiring oophorectomy may be advocated. However, this option is currently under experimental evaluation, and few centers offer this to patients.

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