References

1. Nowell PC, Hungerford DA: A minute chromosome in human chronic granulocytic leukemia. Science 132:1497, 1960.

2. Deininger M, Goldman JM, Melo JV: The molecular biology of chronic myeloid leukemia. Blood 96:3343-3356, 2000.

3. Kralovics R, Passamonti F, Buser AS, et al.: A gain-of-function mutation of JAK2 myeloproliferative disorders. N Engl J Med 352:1779-1790, 2005.

4. Baxter EJ, Scott LM, Campbell PJ, et al.: Acquired mutation of the tyrosine kinase JAK2 in human myeloprolif-erative disorders. Lancet 365:1054-1061, 2005.

5. Levine RL, Wadleigh M, Cools J, et al.: Activating mutation in the tyrosine kinase JAK2 in polycythemia, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7:387-397, 2005.

6. Groffen J, Heisterkamp, N. The chimeric BCR-ABL gene. Baillière's Clin Hematol 10:187, 1997.

7. Mughal TI, Goldman JM: Chronic myeloid leukemia: current status and controversies. Oncology 18:837-854, 2004.

8. Morrison VA: Chronic leukemias. Cancer J Clin 44:353, 1994.

9. Muir CS, Waterhouse J, Mack T, Powell J, Whelan S: Cancer incidence in 5 continents, vol 5. IARC Scientific Publication no. 88. Lyon: International Agency for Research on Cancer, 1987.

Table 16.3 WHO classification of myelodysplastic/myeloproliferative diseases

Chronic myelomonocytic leukemia Atypical chronic myeloid leukemia Juvenile myelomonocytic leukemia Myelodysplastic/myeloproliferative disease, unclassifiable p23018; currently fewer than 100 patients with Ph-positive CNL have been reported worldwide. CNL affects older adults, compared to CML. It is of considerable interest that in about 20% of the reported cases, there was an associated malignancy, typically multiple myeloma, but none of these patients exhibited clonal-ity in their myeloid cells. Distinctions among chronic phase, accelerated phase, and blast crisis CML are discussed in Chapter 17.

10. Court Brown W, Abbatt J: Mortality from cancer causes after radiotherapy for ankylosing spondylitis. Br Med J 2:1327-1329, 1965.

11. Doll R, Smith PG: The long term effects of X-irradiation in patients treated for metropathia haemorrhagica. Br J Radiol 41:362-368, 1968.

12. Heyssel R, Brill B, Woodbury L: Leukemia in Hiroshima atomic bomb survivors. Blood 15:313-331, 1960.

13. Kato H, Schull WJ: Studies on the mortality of A-bomb survivors 1950-1971. Radiat Res 90:395, 1982.

14. Eglin RP, Swann RA, Isaacs D, Moon ER: Chronic leukaemia in siblings. Lancet 2:984, 1984.

15. Posthuma EFM, Falkenburg JHF, Apperley JF, et al.: On behalf of the Chronic Leukemia Working Party of the EBMT. HLA-B8 and the HLA-A3 co expressed with HLA-B8 are associated with a reduced risk of the development of chronic myeloid leukemia. Blood 93:3863-3865, 1999.

16. Marmont A, et al.: Recurrence of PhMeukemia in donor cells after marrow transplantation for chronic granulo-cytic leukemia. N Engl J Med 31:990, 1988.

17. Jaffe ES, Harris NL, Stein H, Vardiman JW (eds.): World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001, pp. 15-60.

18. Melo JV: The diversity of the BCR-ABL fusion proteins and their relationship to leukemia phenotype. Blood 96: 3343-3356, 2000.

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Chapter 17

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

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