Reproducibility And Clinical Relevance

The value of any lymphoma classification is only as good as its histopathological reproducibility and its clinical relevance. In this respect, the validity of the REAL and WHO classifications had already been tested to a certain extent prior to their publication since many of the entities had been subject to detailed clinicopathological analysis in the medical literature. Shortly after its publication, moreover, the reproducibility and clinical relevance of the REAL classification were formally evaluated.

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