The Structure Of The Who Classification

As in the Kiel classification, the lymphomas, defined according to the principles described above, are firstly divided broadly into B- and T-cell groups (Table 51.1). A modification is the inclusion of lymphomas with a NK-cell phenotype in the T-cell group. In each of these two groups the precursor cell, or lymphoblastic, lymphomas are separated from the larger group of peripheral cell tumors. The order in which the different entities are cited is not fixed and can be changed according to the convenience of the user. For example, the B-cell lymphomas can be grouped into those with peripheral blood involvement, plasma cell neoplasms, extranodal lymphomas, nodal lymphomas, and lymphoproliferative disorders of uncertain malignant potential. The T/NK-cell lymphomas are often similarly grouped into those that tend to involve the peripheral blood, cutaneous lymphomas, other extran-odal lymphomas, nodal lymphomas, and a single entity of uncertain lineage.

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