Therapy Of Constitutional Symptoms

MMM is variably associated with a wide range of constitutional symptoms. The most common of these is fatigue, which can range from mild to debilitating. Patients may also suffer from hypercatabolic symptoms, manifested as night sweats, fevers, and significant loss of lean body mass. Lastly, patients occasionally suffer from bone pain that can be severe. There have not been many therapeutic agents, either tested or reported, to significantly palliate these problems. Indeed, these symptoms frequently can be the most debilitating and frustrating to arise in MMM patients.

XRT for palliating extramedullary hematopoiesis in patients with MMM

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