Treatment Approach For Patients With

Once we have made an assessment that a patient with CLL, who has been on a "wait and watch" method of follow-up, should start cytotoxic therapy, we first try to determine what our therapeutic endpoint should be. This assessment is made on a case-by-case basis and, therefore, is highly individualized. For example, for a relatively young patient with no other major comorbid conditions, we would take an aggressive approach with an intent to achieve a complete remission or a good quality partial remission, and then, as the next step, depending upon the ability of the

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