Treatment Of Advanced Stage Mycosis Fungoidesszary Syndrome

Patients may ultimately progress into more aggressive and advanced disease with either cutaneous or extracu-taneous tumor manifestations. Treatment goals in advanced stages should be to reduce tumor burden, to relieve symptoms, to decrease the risk of transformation into aggressive lymphoma, and to preserve quality of life. Standard methods include mono- or poly-chemotherapy, extracorporeal photopheresis, interferons, retinoids, monoclonal antibodies, recombinant toxins, combination therapy, and high-dose chemotherapy with allogeneic stem cell transplant.

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