Ucb Banking

Given today's population dynamics, the estimated probability of any patient obtaining an HLA-matched related-donor HSC unit is approximately 30-40%.8 The likelihood of securing a matched unrelated donor unit varies according to ancestry and is less likely in patients of certain racial and ethnic backgrounds. As such, approximately 50% of all patients requiring allo-geneic transplantation are unable to secure an unrelated HLA-matched donor unit.9 As an alternative source of HSC, UCB has the potential to alleviate this donor shortage. UCB banks have been developed to optimize the chances of finding a suitable donor for allogeneic transplantation. Netcord, a cooperative network of large experienced UCB banks in the United States, Europe, Japan, and Australia was founded in 1998 to establish minimum UCBT standards, reach an international agreement on aspects that protect the infant donor and mother, and facilitate the matching process. As of March 2004, over 150,000 UCB units have been banked in 36 UCB registries throughout 21 countries.10

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