Dosage

Cladribine (2-chlorode-oxyadenosine, 2-CdA)

REF: Piro et al. NEJM 1990; 322:1117-1121 Single 7 day infusion days 1-7

Interferon alfa-2a (IFN)

IFN 2 MIU/M2 SQ TIW for 1 year

REF: Rai et al. Leukemia 1995; 9:1116-1120 PREMEDICATIONS

1. Acetaminophen as needed to alleviate fever or "flu-like" symptoms

Pentostatin (2-deoxyco-formycin)

Pentostatin 4 mg/M2 IV

REF: Grever et al. J Clin Oncol 1995; 13:974-982 Repeat every 14 days for at least 3 months day 1

tu tD

Hodgkin's Disease

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