Chlamydial Life Cycle And Persistence

Chlamydia Persistence Cycle

Chlamydiae exhibit a unique obligate intracellular life cycle that is essential for understanding their virulence in both acute and chronic disease. These bacteria have a biphasic life cycle that alternates between a metabolically inert, infectious elementary body EB and a noninfectious, metabolically active reticulate body RB see ref. 12 for review . The molecular events of chlamy-dial growth and differentiation have yet to be defined, but their intracellular life cycle has been sufficiently...