Anorexia Nausea and Vomiting

Anorexia is common in patients on IFN, with loss of appetite and associated early satiety. Patients are frequently told to expect a 5-10% weight loss while on treatment with IFN. In overweight patients with hepatic steatosis, this weight loss can actually be beneficial, but some patients, particularly those with cirrhosis and catabolic malnutrition, do poorly with this degree of weight loss. Frequent small meals and use of high-calorie nutritional supplements are occasionally necessary. If patients lose more than 10% body wt, or have any associated symptoms suggestive of more serious disease, then a clinically appropriate workup for occult malignancy may be necessary.

Nausea and vomiting are dose-dependent side effects of IFN therapy, and can be managed with dietary manipulation and use of antiemetics, such as Reglan or compazine, on a prn basis. In a small subset of patients, nausea and vomiting may be so severe that therapy must be stopped.

Breaking Bulimia

Breaking Bulimia

We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.

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