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FIGURE 4.15 The respiratory clock. This diagram of the rodent brain shows the location of conglomerates of respiratory bulbospinal premotor neurons (i.e., neurons that control nerves responsible for breathing movements). Note: BotC = Botzinger complex, preBotC = pre-Botzinger complex, pre-I = neurons with preinspiratory discharge patterns, rVRG = rostral ventral respiratory group. (Source: Adapted from Feldman, J. L., Mitchell, G. S. & Nattie, E. E. (2003). Breathing: rhythmicity, plasticity, chemosensitivity. Annual Review of Neuroscience 26: 239-266.)

FIGURE 4.15 The respiratory clock. This diagram of the rodent brain shows the location of conglomerates of respiratory bulbospinal premotor neurons (i.e., neurons that control nerves responsible for breathing movements). Note: BotC = Botzinger complex, preBotC = pre-Botzinger complex, pre-I = neurons with preinspiratory discharge patterns, rVRG = rostral ventral respiratory group. (Source: Adapted from Feldman, J. L., Mitchell, G. S. & Nattie, E. E. (2003). Breathing: rhythmicity, plasticity, chemosensitivity. Annual Review of Neuroscience 26: 239-266.)

emerges from the interaction of many cells that are not individually rhythmic.

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