Sickle Cell Anemia

Patients with sickle cell anemia are more fragile on cardiopulmonary bypass. It is crucial to keep the oxygen and pH adequate. Acidosis shifts the oxygen/hemoglobin dissociation curve to the right, thus unloading the red blood cell of oxygen resulting in sickling of the red blood cell. If sickling occurs intraopera-tively on cardiopulmonary bypass, increased mechanical fragility of the walls and trauma of bypass may increase hemolysis. Some sickling is reversible by simply increasing oxygenation. Even the sickle cell trait may result in sickling and cause organic infarct under cardiopulmonary bypass.

Your Heart and Nutrition

Your Heart and Nutrition

Prevention is better than a cure. Learn how to cherish your heart by taking the necessary means to keep it pumping healthily and steadily through your life.

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