Use in Prevention and Therapy

Detoxification. Riboflavin helps the liver detoxify chemicals, pesticides, and other environmental toxins.

Antioxidant functions. Riboflavin functions as an antioxidant throughout the body and may be especially important in the lens of the eye. Ample intake of riboflavin can reduce the risk of developing cataract. As a cofactor of glutathione reductase, riboflavin helps maintain the body's supply of reduced glutathione, an important antioxidant.1

Skin and mucous membranes. Ample ribo-flavin intake maintains the health of the skin and mucous membranes.5 It may be beneficial in stomatitis, cheilosis, and skin eruptions and rashes.

Fatigue and depression. In people with increased riboflavin requirements, dietary inadequacy may produce a subclinical deficiency that causes fatigue, depression, and personality changes.6 This may respond to ri-boflavin supplementation.


There are no reports of toxicity associated with riboflavin supplementation. Large doses of riboflavin will produce a harmless yellow color in the urine.

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