Sedative Hypnotics

Benzodiazepines impair psychomotor performance in nontolerant individuals, generally in a dose-dependent manner. Most of the widely prescribed benzodiazepines increase lateral lane movement and slow response time to a lead car's change in speed. Several of the benzodiazepines (50 mg of oxazepam, 30 mg of flurazepam, and 2 mg of lormetazepam) predictably impair driving the morning after. Diazepam (15 mg) impaired performance on a clinical test for drunkenness, which comprised 13 tests assessing motor, vestibular, mental, and behavioral functioning (78,79). A recent study (80) showed a clear relationship between dose of benzodiazepines and risk of impairment, which the authors believed probably supported a limit for benzodiazepines and driving as low as within the therapeutic range.

Acute doses of many benzodiazepines slow response time in simple or choice visual reaction time tests and impair attentional performance and cause deficits that do not result from sedation. In fact, the impairment of sustained attention and vigilance in benzodiazepine users is the direct result of some as yet uncharacterized direct action on perceptual sensitivity (70).

Conquering Fear In The 21th Century

Conquering Fear In The 21th Century

The Ultimate Guide To Overcoming Fear And Getting Breakthroughs. Fear is without doubt among the strongest and most influential emotional responses we have, and it may act as both a protective and destructive force depending upon the situation.

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