Symptoms and Complications

After an incubation period of 6-8 weeks, the acute phase of the disease lasts approx 2-3 years. Unlike hepatitis A (HAV) or HBV, the patient is usually asymptomatic; therefore, the disease is often missed unless the individual has reported a specific exposure and is being monitored. Other cases are found by chance, when raised liver enzymes are found on a routine blood test.

A "silent phase" follows the acute phase when the virus lies dormant and the liver enzymes are usually normal. This period lasts approx 10-15 years. Reactivation may then occur. Subsequent viral replication damages the hepato-cytes, and liver enzymes rise to moderate or high levels.

Eighty percent of individuals who are HCV antibody-positive are infectious, regardless of the levels of their liver enzymes. Approximately 80% of people develop chronic infection, one-fifth of whom progress to cirrhosis. There is a much stronger association with hepatocellular carcinoma than with HBV. An estimated 1.25-2.5% of patients with HCV-related cirrhosis develop liver cancer (18). Less than 2% of chronic cases resolve spontaneously.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

Get My Free Ebook

Post a comment