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Multiple Choice Questions

1. Mast cell derived histamine induces vasodilatation. Which of the following inflammatory mediators induce degranulation of mast cells and histamine release?

a. Crosslinking of IgE bound to mast cell FceR

b. Binding of complement fragment C3a c. Binding of complement fragment C5a d. All of the above e. Only a and c

2. Activation of the contact system leading to coagulation during tissue damage leads to the generation of bradykinin. Bradykinin is a fragment derived from which one of the following.

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