Growth Factors

This section includes information on some of the specific proteins used as supplements, which are often added to cell culture media in order to enhance cell growth. These components are supplements to basal media that will promote growth in the absence of serum or in reduced serum formulations.

Many polypeptides have been characterized as mitogenic in vitro for specific mammalian cell lines. This family includes fibroblast growth factor (FGF: aFGF and bFGF), insulin-like growth factor (IGF), epithelial growth factor (EGF), nerve growth factor (NGF), platelet-derived growth factor (PDGF), and transforming growth factor (TGF: a and b). These growth factors are active in the 1-10 ng/mL range.

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