Packed Bed Bioreactors

Fixed bed or packed beds are an alternative bioreactor technology to fluidized beds for the immobilization of cells. Both terms are used as synonyms for immobilization systems that have been deduced from large-scale fixed bed reactors ori-

Table 4 Applications of Fluidized Bed Bioreactor Systems

Reactor type

Microcarrier type

Microcarrier properties: average diameter (mm); pore diameter (|^m)

Cell line

Cell density (106/mL settled bed volume)




Verax microspheres

0.5; 20^10

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