Accelerated Muscular Development Programs

Isometrics for Mass and Body Fat Loss

Isometric Mass is the most revolutionary fitness program in the market right now. It is the great way of training to build muscle in short time and increase the testosterone in the blood, a way that proved to help even 40th and 50th men to overcome their age boundaries and build beautiful muscle and improve their health with less than 30 min training every day. Isometric mass program helped me build muscle with less effort in less time and saved me time and money because the isometric system doesn't need fancy equipment and count only on body weight. The program is divided into basic set of DVDs and bonus set. The basic set cover everything from quick start guide, instructional video library for the isometric techniques, isometric mass workout guide which will save you all your costs you used to pay for trainers and gym. The last basic product is an isometric printable logs to help you keep track of your workout and progress. The bonus part of the isometric mass is very cool because it contain the body weight edition of the isometric system, a great done-for-you meal plan that fits greatly into the isometric system and the last bonus product is a great guide for using supplements which could make you finally understand the art and science of taking supplements. Isometric mass is a great program every muscle builder should have. Continue reading...

Isometrics Mass Summary


4.9 stars out of 30 votes

Contents: Ebooks, Videos, Meal Plan
Author: Alby Gonzalez
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My Isometrics Mass Review

Highly Recommended

The writer presents a well detailed summery of the major headings. As a professional in this field, I must say that the points shared in this manual are precise.

When compared to other ebooks and paper publications I have read, I consider this to be the bible for this topic. Get this and you will never regret the decision.

Massthetic Muscle

Massthetic Muscle is a 12 week training block scientifically programmed into 3 detailed training cycles (Initiation, Growth, Targeted). To ensure that each and every workout is of maximum efficiency and designed in a way to optimally achieve the goal within the given cycle, Massthetic Muscle was programmed and written using the fundamentals within our proprietary Precision Hypertrophy Principles (PHP). These principles take into account the relationship between strength profiles, resistance profiles, and active ranges of motion for all exercises and muscles. They integrate various approaches and applications of training (compound lifts, machines, cables, free weights, and multiple intensifying techniques) to create the perfect anabolic environment and stimulate the right amount of muscle fiber damage to maximize strength and muscle gains, all at the same time producing a hormonal effect that will ignite fat loss. This is not a program for someone who is looking for an easy solution to muscle building. It requires Intense work. Continue reading...

Massthetic Muscle Summary

Contents: Ebooks
Author: Frank Rich
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The Muscle Maximizer

The first truly custom, interactive, professional nutrition system proven to explode lean muscle growth without any fat. The systems 4 patented formulas are the true keys to unlocking more muscle growth than you thought possible. Formula 1 is the Sometabolic Customizer You will discover your exact calorie and macronutrient needs to build pure lean muscle using the systems advanced somatotyping techniques. You will also find out exactly what and when to eat based around your weight training regimen to catapult your body into a 24/7 muscle building state. Formula 2 is the Somanabolic Rebuilder This is for your off days. Your recovery nutrition is custom structured to repair and rebuild your broken down muscle tissue quickly. Using unique calorie and macronutrient shifting techniques your muscle recovery is extremely rapid and muscle soreness is often 100 % eliminated. Formula 3 is the ever so important Systematic Nutrabolism This is the key for up to 84% of all your lean muscle growth. Continue reading...

The Muscle Maximizer Summary

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Adonis Golden Ratio System

This system is designed and guaranteed to quickly kill your stubborn stomach fat and deliver your leanest, most muscular physique genetically possible without drugs. You will be teached how to easily take your current measurements to determine how close to The Adonis Golden Ratio you are so you have a starting point. This measurement is called your Adonis Index and will be used to determine every aspect of the custom 12 week Adonis Golden Ratio program. Then youll use a custom 12 week training, nutrition and supplementation blueprint for rapid and targeted muscle building and fat loss to achieve your very own. Continue reading...

Adonis Golden Ratio System Summary

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Creator: Kyle Leon
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Skeletal Muscle Development

Glypican-1 expression has been identified during skeletal muscle development (96). During skeletal muscle formation, syndecan-1 levels are high during the proliferation of muscle cells followed by an increase in glypican-1 expression during muscle cell differentiation (82). Both syndecan-1 and glypican-1 function in the signaling of FGF-2. Fibroblast growth factor 2 is a potent stimulator of muscle cell proliferation and a strong inhibitor of muscle cell differentiation. The differences in syndecan-1 and glypican-1 expression suggest that these proteoglycans function in a differential manner in the signaling of FGF-2. Brandan and Larrain (73) hypothesized, based on differences in their in vitro expression in myogenic cell cultures, that syndecan-1 may increase muscle cell proliferation by presenting FGF-2 to its receptor, and glypican may sequester FGF-2 to permit differentiation to proceed. Conclusive evidence has not yet been obtained to support this hypothesis. Syndecans-2 through...

Exercise Training in Chronic Heart Failure

As suggested by the association between low serum insulin-like growth factor I (IGF-I) levels and loss of lean muscle mass, patients with CHF suffer from a clinically relevant imbalance between anabolic and catabolic influences on the peripheral muscle.49 In skeletal muscle biopsies of non-cachectic patients with CHF, the local IGF-I expression was substantially reduced despite normal growth hormone (GH) and IGF-I serum concentrations.50 It has been previously shown that a state of GH resistance may develop in cardiac cachexia. Exercise training has the potential to increase local IGF-I expression and to reverse muscle catabolism.

Functional Decline and Aging

Maximal oxygen consumption (VO2max) declines with age at a rate of 3-8 per decade beginning at 30 years of age 30, 31 . While the major contributor to VO2max is lean muscle mass, after correction for muscle mass, there is no important decline in VO2max with aging 32 . Physically active older men have a higher VO2max

The Role Of Thymosin Family Actinbinding Proteins In Actin Dynamics

This mRNA is also found in certain tissues, including mesenchymal tissues and the spinal cord, in 9.5 to 12.5-day old embryos. These authors have also encountered differences in the distribution of TP4 and TP 10 mRNAs, which could conceivably suggest differences in their function in embryonic development. TP4 has been detected in early chick embryo cells but not in adult skeletal muscle cells. Cofilin also is associated with muscle development, but its relative contribution may change during muscle development (Nagaoka et al. 1996). These observations are consistent with the notion of development-related expression of thymosins.

Arthrogryposis multiplex congenita

Arthrogryposis is characterized by multiple congenital joint contractures and hypoplastic musculature. Although the cause is unknown, several theories have been proposed, including viral infection of the central nervous system, anterior horn cell degeneration, and embryonic arrest of muscle development 35 . Conditions such as oligohydramnios and increased intrauter-ine pressure, which result in decreased embryonic movement in utero, have also been suggested as possible contributing factors. Administering

Creatinine Metabolism

Creatine is synthesized in the liver, pancreas, and kidneys from the amino acids arginine, glycine, and methionine. Creatine is transported through the circulatory system to muscle, brain, and other organs, where it is converted to phosphocrea-tine and acts as an energy reservoir much like ATP. Creatinine is produced as a waste product of creatine and phosphocreatine. Because much of the creatinine is produced in muscle, the amount of creatinine that is measured in blood is proportional to the patient's lean muscle mass. The waste product, creatinine, enters the blood supply, where it is removed through the kidneys.

Glomerular function Glomerular filtration

Cystatin C is a naturally circulating, low molecular weight, basic protein which is freely filtered by the glomerulus and almost completely reabsorbed and catabolised by tubular cells. Serum levels are independent of age, sex and lean muscle mass. Although levels reflect trends in reduced GFR, particularly < 40 ml min 1.73 m2, there is doubt about cystatin C's ability to detect changes in GFR before the serum creatinine has risen (Odoze et al. 2001 Laterza et al. 2002 Mussap et al. 2002 Tan et al. 2002 Buysschaert et al. 2003 Harmoinen et al. 2003 Christensson et al. 2004 Perkins et al. 2005). Also, measurement may be affected by non-renal factors (Harmoinen et al. 1999). Given this uncertainty, it seems premature to recommend the use of cystatin C as a marker of GFR.

P2X Signalling and Development

Activity-driven Ca2+ influx into the cell can lead to the induction of the new gene transcription70 required to shape and wire the brain during development. Ca2+ spikes and waves directly control neuritogenesis in cultures of amphibian spinal neurons.71'72 Intracellular Ca2+ spikes can modulate neuronal migration73 or neurogenesis of neocortical precursor cells.74 P2X receptors have been repeatedly indicated to play a role in development.75'4 Therefore, Ca2+ influx through the P2X receptors appears to be a promising field of CNS development research. In the chick embryo P2X receptor subunits are expressed at early stages of skeletal muscle development the expression disappears before the stage in which myoblasts fuse to form myotubes.76 P2X, and P2X2 receptor subunits were shown to play a key role in the development of afferent and efferent innervation and morphogenesis of the cochlea.77'78 P2X receptor subunit expression presents specific localisations in definite developmental time...

Jrg A Gasser 1 Introduction

Quantitative computed tomography (QCT) is an established technique for the determination of bone mineral density (BMD) in the axial and appendicular skeleton (1). QCT is unique amongst methods of bone mineral measurement in providing separate estimates of trabecular and cortical bone mineral density as a true volumetric mineral density value (g cm3) (2). In addition, QCT can measure geometric properties of cortical bone with great accuracy (3) and predict some mechanical properties with remarkable precision (4-6). Peripheral quantitative computed tomography (pQCT) is a special type of computed tomography in which scans of the appendicular skeleton are performed at a low radiation dosage. Bone and muscle development can be assessed noninvasively by pQCT at peripheral sites in studies of bone development, experimental models of bone loss, and in monitoring the effectiveness of therapeutic interventions. In addition, pQCT can be used to assess excised bones ex vivo from virtually any...

Growth Hormone and Insulin Like Growth Factor1

Growth hormone (GH) and insulin-like growth factor (IGF)-1 stimulate amino-acid uptake and protein synthesis in muscle and improve myocyte proliferation and differentiation in animal studies 106, 107 . The FDA recently granted accelerated approval for a form of recombinant human GH (rhGH) to treat AIDS wasting. Preliminary reports from Schambelan and co-workers in AIDS patients have all been positive 108-112 . The combined GH and IGF-1 doses used in studies in adult males with HIV-associated weight loss had mixed results in producing a sustained anabolic response 113-120 . In fact, after trauma, the anti-catabolic action of rhGH is associated with a potentially harmful decrease in muscle glutamine production and increased mortality 116 . Use of the rhGH for elderly patients with a low somatomedin C or IGF improved lean muscle mass, but not functional ability. Moreover, frequent side effects were seen 121 . Morley and coworkers 122 demonstrated that rhGH, which is a very expensive...

Epigenetic Basis Of Disease

Apart from this HDACs are also associated with a number of other epigenetic repression mechanisms including histone methylation, polycomb group of proteins and DNA methylation (discussed later). The class II HDACs have been found to be involved in muscle development, particularly HDAC 5 and 9 knockouts or mutants show evidence of cardiac hypertrophy in a age or stress dependent manner (Zhang et al., 2002 Chang et al., 2004).

Body Mass Index

Lean muscle mass, serum albumin levels, oxygen expenditure, hydrostatic weight measurement, potassium and water content. A statistically significant correlation of BMI and morbidity-mortality from all causes, diabetes, cardiovascular and infectious diseases, and cancer has been shown by unequivocal studies.


Fibroblast growth factor-2 is a heparin-binding growth factor that stimulates cell proliferation and inhibits cell differentiation. Although FGF can bind to its tyrosine kinase receptor, the low-affinity interaction with heparan sulfate enables the formation of a high-affinity interaction with its receptor, resulting in growth factor mediated signaling at low growth factor concentrations. The interaction of syndecan-1 with FGF has been shown to play a role in skeletal muscle development (42), and wound repair (55). During wound repair, syndecan-1 expression is induced by FGF-2 (56). A 280 bp sequence located -10 kb from the syndecan-1 translation initiation site functions as a promoter element for the syndecan-1 response to FGF-2. This 280 bp domain is termed the fibroblast growth factor-inducible response element. To date, similar elements have not been reported for syndecans 2 through 4.

Tendon Biomechanics

FIGURE 5.1 Sarcomere length-tension curve elucidated for isolated frog skeletal muscle fibers by Gordon, Huxley, and Julian 1966 . This demonstrates the length dependence of skeletal muscle on isometric strength. FIGURE 5.1 Sarcomere length-tension curve elucidated for isolated frog skeletal muscle fibers by Gordon, Huxley, and Julian 1966 . This demonstrates the length dependence of skeletal muscle on isometric strength.

Physical Activity

A comprehensive exercise program for elderly patients includes activities to develop strength, endurance, flexibility, and coordination in a progressive and enjoyable way. It must use all major muscle groups in exercises that train through each individual's fullest possible pain-free ranges of movement. An exercise program for elderly patients must also aim to load the bones target major functional, postural and pelvic floor muscles include practice of functional movements and emphasize the development of body awareness and balance skill. A combination of regular recreational walking and water gymnastics (both at an intensity that is comfortably challenging), preferably combined with specific exercises to improve strength and flexibility such as weight training, circuit training, step training, exercise to music, dancing, and Qi Gong,34 will meet most of these criteria for most people.

Muscle testing

Dynamometer Machine Isokinetic

One-repetition maximum weightlifting. For isotonic muscle force, one-repetition maximum (1-RM) weightlifting is a dynamic method for measuring the maximum amount of weight lifted on a single repetition during a standard weightlifting exercise. In order to achieve the maximum lift capacity, weight increments of 1-5 kg are typically used, with intervals of 1-5 min between attempts. In elderly people, 1-RM can be calculated from submaximal efforts 77 . For untrained persons, the calculated 1-RM (kg) is 1.554 x (7-10-RM)-5.181, where 7-10-RM represents a set of 7-10 repetitions. The 7-10-RM weight (kg) represents 70 of the 1-RM. For trained persons, the calculated 1-RM is 1.172 x 7-10-RM+7.704, with the 7-10-RM representing 80 of the 1-RM. slightly. Both tests are reproducible, but higher values have been obtained during break tests 86 . Hand-held dynamometry is a viable alternative to more costly modes of isometric strength measurement, provided the assessor's strength is greater than...

The Basics Of Body Building

The Basics Of Body Building

Bodybuilding is the process of developing muscle fibers through various techniques. It is achieved through muscle conditioning, weight training, increased calorie intake, and resting your body as it repairs and heals itself, before restarting your workout routine.

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