Acute Aseptic Meningitis Encephalitis and Myelitis Clinical Features

Meningitis presents with fever, general malaise, headaches, photophobia, nuchal rigidity, nausea, vomiting, and muscle aches. Altered states of consciousness, focal neurologic deficits, and seizures are common in encephalitis. Flaccid mono- or paraparesis suggests myelitis. The CSF yields a mild to moderate pleocytosis, typically with lymphocytes; however, during the initial stage, PNLs may also be present. Protein is moderately elevated and glucose is normal. Viral-specific DNA and RNA are identified in the CSF and blood using PCR assay and in-situ hybridization.

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