Congenital And Neonatal Infections

The most common pathogens of congenital and neonatal infections are viruses and the protozoa Toxoplasma gondii. Bacteria and the spirochete Treponema pallidum are less common. (See Chapter 6 on infectious diseases.) Fetuses are infected transplacentally, and neo-nates are infected during delivery through an infected birth canal or by breast feeding with infected milk. The maternal infection may be acutely acquired or more often results from reactivation of a clinically latent infection. Infections during the first trimester produce the most widespread injuries, notably inflammatory destructive lesions in the brain, sensory organs, and viscera, and malformations (Table 14.4). Among the major malformations are hydranencephaly, polymicro-gyria, hydrocephalus, and microcephaly. The neurologic sequelae of infections acquired later in gestation are mental retardation; visual, auditory, and motor deficits; and seizures. Maternal infections are diagnosed by sero-logic tests, and fetal infections are diagnosed using poly-merase chain reaction (PCR) assay.

Pregnancy And Childbirth

Pregnancy And Childbirth

If Pregnancy Is Something That Frightens You, It's Time To Convert Your Fear Into Joy. Ready To Give Birth To A Child? Is The New Status Hitting Your State Of Mind? Are You Still Scared To Undergo All The Pain That Your Best Friend Underwent Just A Few Days Back? Not Convinced With The Answers Given By The Experts?

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