Epidermoid Cysts

This tumor-like lesion occurs chiefly in adults, usually in the cerebello-pontine angle, the parasellar region, or in the diploe of the skull.

Grossly, the cyst wall is smooth or nodular and contains white, glossy material resembling mother of pearl (pearly tumor) (Fig. 11.38). Histologically, the fibrous capsule is lined with stratified squamous epithelial cells, and the tumor contains concentrically arranged keratin from the desquamation of squamous epithelial cells. If the capsule breaks, the contents evoke a granu-lomatous aseptic meningitis and ependymitis with foreign-body giant cells (see Fig. 11.38).

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