Friedreichs Ataxia Clinical Features

Friedreich's ataxia (FA) presents during childhood or adolescence with gait and limb ataxia, loss of sense of joint position and vibration, and loss of tendon reflexes. During the course of the disease, which averages from 20 to 25 years, optic atrophy, sensorineural hearing impairment, weakness and spasticity in lower extremities, Babinski sign, and dysarthria develop. Characteristic systemic manifestations include skeletal anomalies with scoliosis and pes cavus, hypertrophic cardiomyop-athy, and occasional diabetes mellitus. FA, an autosomal recessive disease, is caused by an expansion of guanine-adenine-adenine (GAA) repeats in the frataxin gene on chromosome 9. Expansion of the repeats is from 90 to more than 100. The normal number of repeats is 6 to 27.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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