Hypoxic Ischemic Parenchymal Necrosis

The lesions of hypoxic-ischemic insult may involve either the cerebral cortex, the white matter, or both.

Periventricular leukomalacia, a typical white matter lesion in neonates, is situated in front of or around the anterior horns; it may extend posteriorly along the ventricular walls. Grossly, the periventricular white matter is yellow, soft, and chalky (Fig. 14.3). Histologi-cally, the necrotic tissue is invaded by macrophages and, in time, is replaced by a glial scar or a small cavity. Diffuse white matter changes interfere with myelination by affecting the premyelinating oligodendrocytes.

How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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