Myoclonus Epilepsy with Ragged Red Fibers

Myoclonus epilepsy with ragged red fibers (MERRF) affects children and adults. Cardinal clinical manifestations include short stature, seizures, polymyoclonus, optic atrophy, sensory-neuronal hearing loss, cerebellar ataxia, peripheral neuropathy, and myopathy. The disease is maternally transmitted and is associated with point mutations in tRNA gene.

The pathology consists of (a)neuronal degenerations and gliosis in the dentate nuclei and cortex of the cerebellum, inferior olivary nuclei, red nucleus, substantia nigra, globus pallidus, and Clarke nucleus of the spinal cord; (b) demyelination of the superior cerebellar peduncles and posterior columns and spinocerebellar tracts of the spinal cord; and (c) ragged-red fiber myopathy.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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