Neuroacanthocytosis

This disease is characterized by choreiform movements, dystonia, orofacial dyskinesia, cognitive deficit, peripheral neuropathy, seizures, and acanthocytosis (thorny erythrocytes) in the peripheral blood, and a normal lipoprotein concentration. It is inherited in an autosomal recessive or dominant fashion and affects individuals in the third and fourth decades. Neuronal losses in the striatum and, to a lesser degree, in the pallidum characterize the pathology.

TABLE 5.15.

Cerebellar and Spinocerebellar Degenerations

Hereditary

Autosomal recessive

Friedreich's ataxia Ataxia telangiectasia

Cerebellar ataxia with isolated vitamin E deficiency

Autosomal dominant

Spinocerebellar ataxias Dentatorubro-pallidoluysial atrophy Episodic ataxias

Sporadic

Olivopontocerebellar atrophy Idiopathic cerebellar ataxia

TABLE 5.16.

Trinucleotide Repeat Diseases

Huntington's disease

Bulbospinal muscular atrophy (Kennedy's disease) Friedreich's ataxia Dentatorubropallido-luysial atrophy Adult-onset spinocerebellar ataxias

Peripheral Neuropathy Natural Treatment Options

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