Neurofibromatosis Type 1 NF1 and Neurofibromatosis Type 2 NF2

NF1 and NF2 share several features; both are inherited in an autosomal dominant fashion. About 50% of cases, however, occur sporadically because of a high rate of spontaneous mutations. Tumors of the peripheral nerves are the diagnostic hallmarks of both syndromes. Clinically, they may present from early childhood to adulthood. The expressivity varies from a monosymptomatic abortive form to a broad range of manifestations including seizures, mental retardation, and systemic disorders. T2-weighted MRI may show hyperintense lesions in the white matter and basal ganglia, corresponding to hetero-topia and failure of myelination.

The two syndromes differ in genetic profiles, histo-logic tumor types, and systemic manifestations.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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