Neurofibromatosis Type

The defective gene of this less common hereditary tumor syndrome maps to chromosome 22. The gene product is meslin or schwannomin.

Nervous System Tumors

Characteristic nerve sheath tumors are the schwannomas (neurinomas) of the cranial and spinal nerve roots and peripheral nerves. Bilateral acoustic neurinomas are hallmarks of the syndrome. Additional CNS tumors are the meningiomas, single or multiple, spinal ependy-moma, and astrocytoma. Heterotopia and cerebral cal-cifactions add to the pathology.

Systemic Disorders

Café-au-lait skin pigmentations are less common than in NF1. Posterior subcapsular cataract is the ocular abnormality.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

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