Sarcoidosis, a subacute or chronic inflammatory disease of undetermined etiology, affects the skin, visceral organs, eyes, parotid glands, and lymph nodes. In about 5% of cases, the brain and spinal cord are involved. Clinical features include cranial and peripheral nerve deficits and hypothalamic and pituitary symptoms and signs. The pathology is characterized by a noncaseating granulomatous meningoencephalitis. Grossly, the lepto-meninges are thickened, and the subarachnoid space, mostly at the base of the brain, is filled with a gelatinous exudate. Histologically, noncaseating microgranulomas composed of epithelioid cells, mononuclear cells, and giant cells infiltrate the leptomeninges and underlying parenchyma, the ventricular walls, and the choroid plexus. The brunt of the inflammatory process is at the base, extending into the cranial and peripheral nerve roots.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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