Pathology

The meninges are involved in traumatic, infectious, hemorrhagic, and neoplastic diseases. The epidural and the subdural spaces are common sites of traumatic hemorrhages. The subarachnoid space is the site of exudate from leptomeningeal inflammation, of hemorrhage from rupture of a berry aneurysm, and of neoplastic infiltration from primary or metastatic neoplasms. Postinflammatory and posthemorrhagic fibrosis of the leptomeninges and arachnoid villi interferes with the circulation and absorption of CSF, ultimately leading to hydrocephalus.

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