Perineurinomas Grade

These rare, benign tumors derive from perineural cells and present in two forms, intraneural and soft-tissue perineurinomas.

The intraneural perineurinoma most often affects the peripheral nerves of the extremities of young adults. Grossly, it appears as a focal enlargement of the nerve. The histology is characterized by onion bulb formation; that is, a concentric arrangement of perineural cells around the myelin and axon. The cells immunoreact for epidermal membrane antigen (EMA) and are negative for S-100 protein.

The soft-tissue perineurinoma occurs in the subcutaneous tissue of the extremities, most often in women. The cells form bundles, interwoven fascicles, and whorls.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

Get My Free Ebook


Post a comment