Pineoblastoma Grade

This malignant tumor originates from immature neo-plastic cells of the parenchyma and is more common in children and adolescents. It is fast growing, grossly soft, invasive, and may contain hemorrhages and necrosis. Histologically, pineoblastoma is highly cellular, comprised of small cells arranged in sheets or forming rosettes. The cells tend to seed within the subarachnoid space and metastasize outside the cerebrum. Their immunohistologic reactivities are similar to those of pineocytes (Fig. 11.26B).

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