Trichinosis

Trichinosis, caused by Trichinella spiralis, is acquired through the ingestion of meat contaminated with encysted trichinella larvae. From the intestinal tract, the larvae reach the skeletal muscles, visceral organs, and brain via the bloodstream.

Systemic manifestations include fever, eosinophilia, myalgia, facial edema, and cardiovascular and pulmonary symptoms. Common nervous system manifestations are headaches, seizures, altered mentation, focal

FIGURE 6.32

Cerebral echinococcosis. Hydatid cysts surgically excised from the left frontal lobe of a 32-year-old woman with a 9-month history of seizures, motor and sensory deficits, and aphasia.

FIGURE 6.32

Cerebral echinococcosis. Hydatid cysts surgically excised from the left frontal lobe of a 32-year-old woman with a 9-month history of seizures, motor and sensory deficits, and aphasia.

neurologic signs, cranial nerve deficits, and psychiatric symptoms. Multiple small lesions with ring-like enhancement are evident on CT scan, and small hyperintense white-matter lesions are apparent on MRI. The diagnosis is confirmed using serology tests and muscle biopsy.

The cerebral pathology varies: It can be an eosino-philic meningoencephalitis, or multiple small hemorrhages, infarcts, and granulomas in the gray and white matter.

FIGURE 6.33

Cerebral schistosomiasis. Schistosoma ova in the subarachnoid space (HE).

FIGURE 6.33

Cerebral schistosomiasis. Schistosoma ova in the subarachnoid space (HE).

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