Aidsassociated Necrotizing Ulcerative Periodontitis

dude linear gingival erythema (l oi ). Nl'(ยป. and NUP.*1 I he necrotizing forms appear particularly in severe or advanced immunosuppression, Gingival and periodontal lesions are frequently found in patients with AIDS. These gingival and periodontal lesions in HIV-positive patients appear to be similar to those seen in NUP in 111 \ -negative patients but frequently result in complications that are extremely rare in non-AIDS patients, these complications consist of large areas of soft tissue necrosis with exposure of bone and secpiestration of bone fragments, which sometimes extend to the vestibular area and/or the palate and become necrotizing stomatitis.

Progression

Bone loss associated with HIV-positive NUP may be extremely rapid. Winkler and colleagues'" mention cases in which 10 mm ol bone were lost in 3 months

Etiology

AIDS favors the occurrence ot opportunistic infections leading to Nl o, atypical gingivitis (an aggressive form of chronic periodontitis), and NUP. Murray and co-workers' have reported that cases of NI P in AIDS patients demonstrate greater numbers of the opportunistic fungus ( cmdida albicans and higher prevalence of Acti-iiobacillus iii tinomyi ctemcomitans, PrcvotcUa iiitcrmediii, Porphyromonas gingiva lis, Pusobachrium nuclcatiint, and ( antpylobactcr spp. I hey also observed tli.it the destructive periodontal lesions seen in \ll)S patients differ substantially from NU(i lesions; particularly noteworthy is the low or variable level of spiroc hetes, which is inconsistent with the NUG flora. I he flora found in NUP in AIDS patients is more in line with that of chronic periodontitis.

lor a more detailed description of these diseases, see Chapters IS and ll); treatment is discussed in <.'hapten W and 45.

Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

Get My Free Ebook


Post a comment