Koplik's spots are an early sign of measles (rubeola). Search for small white specks that resemble grains of salt on a red background. They usually appear on the buccal mucosa near the first and second molars. In this photo, look also in the upper third of the mucosa. The rash of measles appears within a day.
Fordyce Spots (Fordyce Granules)
Fordyce spots are normal sebaceous glands that appear as small yellowish spots in the buccal mucosa or on the lips. A worried person who has suddenly noticed them may be reassured. Here they are seen best anterior to the tongue and lower jaw. These spots are usually not so numerous.
Petechiae are small red spots that result when blood escapes from capillaries into the tissues. Petechiae in the buccal mucosa, as shown, are often caused by accidentally biting the cheek. Oral petechiae may be due to infection or decreased platelets, as well as to trauma.
A thickened white patch (leukoplakia) may occur anywhere in the oral mucosa. The extensive example shown on this buccal mucosa resulted from frequent chewing of tobacco, a local irritant. This kind of irritation may lead to cancer.
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