Comprehension Questions

[45.11 An 18-year-old nulliparous female complains of not having started her menses. Her breast development is Tanner stage V. She has a blind vaginal pouch and no cervix. Which of the following is the most likely diagnosis'?

A. Mullerian agenesis

B. Androgen insensitivity

C. Both of the above

D. Neither of the above

|45.2] A 20-year-old GO PO woman is told by her doctor that there is a strong probability that her gonads will turn malignant. She has not had a menses yet. Which of the following is the most likely diagnosis?

A. Mullerian agenesis

B. Androgen insensitivity

C. Both of the above

D. Neither of the above

[45.3] A 19-year-old girl has primary amenorrhea and a pelvic kidney. Which of the following is the most likely diagnosis?

A. Miillerian agenesis

B. Androgen insensitivity

C. Both of the above

D. Neither of the above

[45.4] Which of the following is the best explanation for breast development in a patient with androgen insensitivity?

A. Gonadal production of estrogens

B. Adrenal production of estrogen

C. Breast tissue sensitivity to progesterone

D. Peripheral conversion of androgens

E. Autonomous production of breast-specific estrogen

[45.5] A 15-year-old female is brought to the pediatrician because of absence of breast development and short stature. Karyotype is performed and reveals 46,XY. Which of the following is the most likely diagnosis?

A. Androgen insensitivity

B. Kallmann syndrome

C. Gonadal dysgenesis

D. Testicular atrophy syndrome

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