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Historical References

A specific role for the medical expert as a provider of impartial opinion for the judicial system was identified clearly by the Justinian Laws between 529 and 564 ad. Traill (2) states that Medical Jurisprudence as a science cannot date farther back than the 16th century. He identifies George, Bishop of Bamberg, who proclaimed a penal code in 1507, as the originator of the first codes in which medical evidence was a necessity in certain cases. However, the Constitutio Criminalis Carolina, the code of law published and proclaimed in 1553 in Germany by Emperor Charles V, is considered to have originated legal medicine as a specialty expert medical testimony became a requirement rather than an option in cases of murder, wounding, poisoning, hanging, drowning, infanticide, and abortion (1). Medicolegal autopsies were well documented in parts of Italy and Germany five centuries before the use of such procedures by English coroners. The use of such expertise was not limited to deaths or to...

Ancient Greece And Rome

The use of cannabis in ancient Greece and Rome has been reviewed in detail by Brunner (1973). 'Cannabis' is the Latin word for the hemp plant in ancient Greek it was written K vva ii . None of the ancient Greek or Roman writers have described the intoxicating effects of cannabis upon their own citizens. This leads to the conclusion that the populace was either unaware of the intoxicating effects or chose to abstain from them for some reason. It seems unlikely that either civilisation could have been completely ignorant of this property of cannabis, since the plant was widely used at the height of each civilisation for the production of rope and coarse fabric. Perhaps, like the Chinese, cannabis did not suit the Greek or Roman temperament. Both peoples consumed large amounts of wine, and perhaps cannabis was viewed as a less desirable substitute or was taken only occasionally and in private by a select few. If cannabis was used widely it is not credible that it should go unmentioned by...

Darwins Rising and Falling Fortunes

Darwin had taken a commonsensical approach to laying out natural selection as the means for changing species. In Origin, Darwin argued that if artificial selection in the hands of plant and animal breeders brought about all the changes seen in domesticated breeds, certainly nature could do no less through natural selection. Indeed, nature (God ) could do more it (She He ) could make species out of varieties. To answer the question, What criteria would nature use to select individuals for breeding (in the fashion of plant and animal breeders) Darwin took recourse to the Malthusian struggle for existence or survival in the wake of over-population.15 What is more, Darwin elected a perfectly reasonable gradualism for the instrument of change, although gradualism did not explain the source of ruptures between forms of living things. For support, Darwin touched all the rhetorical bases available to good science, arguing both from the immediately experienced (the empiricism of Herschel) to...

Who Benefits from Guidelines

If patients are not benefiting from guidelines, who is I suppose overworked physicians and physician-extenders perceive a benefit from having things laid out in cookbook form it is a big time saver. This is increasingly important as shrinking Medicare reimbursement has led to higher patient loads and volume of service. But the major beneficiaries are those with large financial stakes the pharmaceutical industry, professional societies, dialysis companies, insurance companies, Centers for Medicare and Medicaide Services (CMS), and the guideline writers all reap considerable financial benefit from the guideline industry.

Establishing Suicide Prevention Contracts

Many writers and clinicians recommend establishing suicide-prevention contracts (Davidson, Wagner, & Range, 1995 Drye, Goulding, & Goulding, 1973). Although most clinicians we know use verbal suicide-prevention contracts, contracts may be formally written as well. The typical contract is a verbal agreement between client and therapist (or interviewer), sometimes sealed with a handshake. The agreement often sounds something like this

Section Ii Basic Components

Even everyday words have stems. For example, in the words singer, writer, and speaker, sing, write, and speak are the stems. In medical terms such as hepatomone, gastrotome, and arthrotome, the hepat (meaning liver), gastr (meaning stomach), and arthr (meaning joint) are

Preamble to the quiet revolution

This analogy involves pillars and arches. The Hungarian-born British writer Arthur Koestler, in his beautifully titled book2 The Ghost in the Machine, described Darwinian natural selection as one of the four great 'pillars of unwisdom'. Now it will be apparent to you from all that has gone before that I believe Koestler was completely wrong in making this pronouncement. Natural selection is, in my view, quite the opposite of what Koestler considered it that is, it is a pillar of wisdom. To be more specific, it is a pillar of scientific wisdom,

Advisors and Contributors

While compiling this volume, the editors relied on the expertise and contributions of the following scholars, teachers, and writers William Arthur Atkins, M.S. Physics and science writer Normal, Illinois Science and technology writer Science and technology writer (Ms. Miller Stacy is winner of the American Medical Writers Association's 2006 Eric W. Martin Award for excellence in medical writing) Canton, GA Science and technology writer

France In The Nineteenth Century

Shortly after the publication of his most renowned work Moreau, together with the writer Th ophile Gautier, established Le Club des Haschischins in about 1846. It was heavily inspired by Marco Polo's tale of Alaodin and the Assassins from six centuries before (Rudgley, 1993). Le Club met initially amidst the decaying splendours of the Hotel Pimodan in Paris, and later in the apartments of Roger de Beauvoir, a wealthy Parisian socialite. At various times, members of Le Club included literary figures such as G rard de Nerval, Honor de Balzac, Hector Horeau and Alexandre Dumas, as well as Boissard de Boisdenier the painter and Charles Baudelaire the poet.

Social learning theory

Some of the concepts are developed by the individual interacting with other aspects of his or her environment. However, much of the time is spent with other people and hence the importance of social communication. The communication may be through the media of course. Nevertheless it originates with other people as writers, teachers, radio or television presenters or actors (see National Institute of Mental Health 1982 Clifford et al 1995). Much communication is non-verbal, in that we observe others undergoing experiences, trying out things, demonstrating things and we learn from that form of communication too. Social learning theory (Bandura 1977) builds on the work of many others to provide a description and an explanation of this process of learning how to behave and how to value things. Others have arrived at similar conclusions from different sources (see, for example, Kelly (1955, 1991) and his study of role relationships, significant others and personal constructs). This...

Suggested Readings And Resources

M., & DeClaire, J. (2001). The relationship cure A five-step guide for building better connections with family, friends, and lovers. New York Crown Publishers. Gottman is currently the premier marriage researcher and writer in the United States. His books are based on his vast research and knowledge of marriage and family functioning. Scarf, M. (1995). Intimate worlds. New York Random House. In this book, popular mental health and relationship writer Maggie Scarf explores family dynamics. Her approach to studying families involves numerous in-depth interviews, and her orientation is generally family systems with a psychodynamic flavor. She emphasizes use of the Beavers Scale of Family Health and Competence for determining levels of family functioning. Scarf is an excellent writer, and this book provides readers with good background information about family functioning from a systems-psychodynamic perspective.

Basal Bodies and Microtubule Organization in Pathogenic Protozoa

The 30 years straddling the end of the 19th and the start of the 20th centuries was a period of intense microscopical and microbiological investigation. This period brought us insights into the biology of the protozoa discovered then to be the etiological agents of major parasitic diseases of man or animals such as Malaria, Leishmaniasis, East Coast fever, Texas or red-water fever and African trypanosomiasis. The sub-structure and activity of living cells was also being described in detail and the protozoa were extremely useful in this endeavor since their unicellularity, coupled with cellular diversity, provided superb experimental material. It is not surprising therefore that in one of the earliest textbooks written at the end of this period Wenyon 1 was able to describe not only the biology of most of the parasitic protozoa that we know today but also many of the features of their cell biology. There was a clear recognition that protozoa exhibited a vast array of filamentous...

Proteomics Clarrification Of Some Misunderstandings

This illustration above vindicates the wisdom of R. A. Fisher that No aphorism is more frequently repeated in connection with field trials, than that we must ask Nature few questions, or ideally, one question at a time. The writer is convinced that this view is wholly mistaken. Nature, he suggests, will respond to a logical and carefully thought-out questionnaire indeed, if we ask her a single question, she will often refuse to answer until some other topic has been discussed (Fisher, 1926). When Gygi et al. (1999) asked if CAI could predict protein production, nature refused to give them the right answer. When they asked if mRNA abundance could predict protein production, they again were given a wrong answer. However, when both mRNA and CAI were taken into account to predict protein production, a very good answer was given (Xia, 2005b).

Death at an Early

Contrary to widely held assumptions, the majority of human fertilized eggs fail to turn into blastocysts and implant in the uterus. Moreover, large numbers of implanting blastocysts do not survive gastrulation. As Lewis Wolpert, the embryologist and popular science writer, reminds us, It is not birth, marriage or death, but gastrulation which is truly the most important time in your life.114 Furthermore, a large number of embryos fail to negotiate the embryo-to-fetus metamorphosis.

Verbal Behavior Some Basic Distinctions

Verbal behavior refers to the vocal, written, gestural and signed behavior of a speaker, writer, or communicator. This behavior operates on the listener, reader, or observer, who arranges for reinforcement of the verbal performance in a particular setting. A woman who is hungry may ask a waiter for the tossed green salad with the egg sandwich. The speaker's behavior affects the listener, who in turn supplies reinforcement (i.e., placing the meal on the table). A similar effect is produced if the woman writes her order on a piece of paper. In this case, the written words function like the spoken ones the waiter reads the order and brings the meal. Verbal behavior therefore expands the ways that humans can produce effects on the world.

Speaking Listening and the Verbal Community

The behavior of the speaker (or writer) is functionally different from the behavior of the listener (or reader). That is, the conditions that regulate speaking are distinct from those that affect listening. In the field of psycholinguistics, the distinction between speaking and listening is often blurred by talking about language encoding and decoding. Since both are treated as aspects of language (i.e., the transmission of meaning), there is little attempt to analyze the separate functions of such behavior. In fact, Skinner (1969) used the term rule-governed behavior to describe the behavior of the listener and verbal behavior to specify the performance of the speaker.

TABLE 91 Classification of Mood Disorders

Biding the emotional roller coaster may be a little scary, but it also seems to endow people with the ability to feel deeply and to express these feelings in ways that have been useful to society. Many religious leaders have struggled with periods of despondency or depression, such as Maimonides, Martin Luther, St. Augustine, St. John of the Cross, or Gerard Manley Hopkins. Problems with mood have been extremely common in artists and writers, such as John Keats, Leo Tolstoy, Ernest Hemingway, William Styron, Robert Lowell, and Sylvia Plath. Mood disorders have affected great leaders and politicians, such as Oliver Cromwell, Abraham Lincoln, and Teddy Roosevelt. These people, and many others who may be less famous but no less important, have turned their capacity to feel deeply into a creative reservoir from which they have given many gifts to human society. As the motto of the National Alliance for the Mentally 111 states People with Mental Illness Enrich Our Lives.

The Fop the Scotsman and the Opium Eater

The artist and writer Thomas Griffiths Wainewright (17941847), moved in aristocratic circles.3 To those who had known him, he was a man of mediocre but varied and serviceable talents, devoured by conceit and a fop in dress and manners. He was a good art critic, championing Turner and Blake when they were unpopular, but in his own work he specialised in drawings of female beauty, in which the voluptuous trembled on the borders of the indelicate, and his writings, under pseudonyms such as Janus Weathercock are highly pretentious, even allowing for the flamboyant style of the day.4 The writer Thomas De Quincey's best-known work is the autobiographical essay, Confessions of an English Opium-Eater but he also wrote another essay, On Murder Considered as One of the Fine Arts (1827 and 1839). The subject matter of the Murder essay seems to us peculiar and tasteless, and struck many people similarly even when first published. De Quincey described the idea of the essay coming to him while...

Neural Circuitry and Mood Disorders

Regions that somehow connect many tiny bits of information from many domains of experience. At a clinical level, a psychiatrist might say that a person develops depression because an early life experience, such as loss of a parent, makes her vulnerable to subsequent rejection or loss. A fullblown depression occurs when a sufficient number of events co-occur. The person who had the early loss may also carry an abnormal gene or two, which predispose to depression. The depression itself is finally triggered when she goes off to college, is isolated from high school friends and family, and gets several bad grades on midterm exams. The feeling of emotional suffocation or despair, which the well-known writer Sylvia Plath described as being suffocated under a bell jar in her autobiographical account of her own depression, sets in. The chain of events just described is not unlike that portrayed in The Bell Jar, since Plath lost her father at an early age and developed her first depression...

Historical Context

The prolific author Aldous Huxley (1894-1963) wrote essays, novels, short stories, poetry, and screenplays. While Brave New World is his best-known novel, others such as Point Counter Point (1928) were successful as well. As is the case with every author, Huxley's background shaped his work. He was born in Surrey, England, on July 26, 1894, the third of four children. His father, Dr. Leonard Huxley, was an author, and his mother, Julia Arnold Huxley, was a girls' school founder. Tragedy befell the household when his mother died ofcancer. Later the 16-year-old Aldous attended Eton but left a year later with the serious eye disease keratitis punctata. He was blind for more than a year, which prevented him from finishing rigorous science training and ended his dream of becoming a medical doctor like his famous grandfather T. H. Huxley. Instead, he received a degree in English literature from Oxford. He married his first wife, Maria, in college, and they had a son. After Maria died in...

Of Adolescent Young Adult Oncology as an Entity

Lescent young adult patients requires an understanding of the process of physical, mental, psychological, and social growth and development 21 . Adolescent services had been in existence in the United States since 1951, when Dr. J. Roswell Gallagher established adolescent medicine and a unit at Boston Children's Hospital 22 . Against this background, the first adolescent oncology unit was established in 1978. Establishment of the unit, where this writer was the director, was by a grant from the National Cancer Institute (NCI). The unit was established through the efforts and support of Dr. James Wallace, then the director of the Division of Cancer Control and Rehabilitation, and endorsement of Dr. Gerald Murphy, then the Institute Director at Roswell Park Memorial Institute. While adolescent medicine as an entity was not new, the idea of a separate unit for adolescent young adult oncology patients was unique. Establishment of a unit specifically dedicated to cancer was received...

Successive approximation See shaping

Verbal behavior refers to the vocal, written, and gestural performances of a speaker, writer, or communicator. This behavior operates on the listener, reader, or observer, who arranges for reinforcement of the verbal performance. Verbal behavior often has indirect affects on the environment. This contrasts with nonverbal behavior, which usually results in direct and automatic consequences. When you walk toward an object, you come closer to it. Verbal behavior, on the other hand, works through its affects on other people. To change the position of a lamp, the speaker states Lift the lamp at the back of the room to a listener, who is inclined to respond. Although verbal behavior is usually equated with speaking, vocal responses are only one of its forms. For example, a person may emit gestures and body movements that indirectly operate on the environment through their effects on others. A frown sets the occasion for others to remove some aversive event, while a smile...

Choosing the Structure and Content of Your Report

For many clients, this section is brief or nonexistent. For others, it is extensive, and you may need to reference other records you've reviewed regarding the client. For example, you might simply make a summary statement such as This client has been seen previously by a number of mental health providers for the treatment of posttraumatic stress disorder, substance abuse, and depression unless there is something in particular about the treatment that warrants specification (e.g., a particular form of treatment, such as dialectical behavior therapy was employed and associated with a positive or negative outcome). In this section, we also include information on any family history of psychiatric problems (although some report writers devote a separate section to this topic).

The Authors

Nottingham is a research entomologist and science writer based in the U.K. His interests include vegetable crop production, plant protection, insect behavior, chemical ecology, and plant genetic modification. At Cambridge University, England, his Ph.D. thesis was on the host plant-finding behavior of phytophagous Diptera. Subsequent research has been conducted within the aphid biology group at Imperial College, London, on aphid behavior and its modification by volatile chemicals, and at the University of Georgia on sweet potato weevil. Dr. Nottingham has published around 25 research papers and several books, including Eat Your Genes How Genetically Modified Food Is Entering Our Diet and the Internet-accessible Beetroot. In addition to books, he also writes reports and articles on agriculture and the environment for the European Service Network and other organizations.

Note Taking

Many therapists and writers have discussed note taking (Benjamin, 1987 Pipes & Davenport, 1999 Shea, 1998). Although some experts recommend that interviewers take notes only after a session has ended, others point out that interviewers do not have perfect memories and thus some ongoing record of the session is desirable (Benjamin, 1987 Shea, 1998). The bottom line is that, in some cases, note taking may offend clients, whereas in other cases, it may enhance rapport and interviewer credibility (Hickling, Hickling, Sison, & Radetsky, 1984). Clients' reactions to note taking are usually a function of their intrapsychic issues, interpersonal dynamics, previous experiences with note-taking behavior, and the tact of the interviewer while taking notes. Because you cannot predict a client's reaction to note taking in advance, you should offer an explanation when you begin taking notes during a session. Shea (1998) recommends the following approach

Response Functions

Behavior is not always composed of discrete responses. In fact, it is better to consider behavior as a performance that follows a specific stimulus and at some point results in a particular consequence. (One memorable three-term notation system used to denote this arrangement is A-B-C, which stands for antecedent, behavior, and consequence as detailed in chap. 13.) Although we will use the term response throughout this book, the term does not always refer to a discrete movement like a muscle twitch or a lever press. A response is an integrated set of movements, or a behavioral performance, that is functionally related to environmental events. In fact, some writers have referred to a behavioral stream into which antecedent and consequence events are inserted.

How OMIM is Curated

OMIM is maintained by a small team of science writers and editorial assistants. The OMIM director oversees the staff and is aided by deputy scientific directors for genes and phenotypes who help with the selection of articles from the literature that warrant inclusion. Twelve Subject Author-Editors (SAEs) also help with reviewing the literature and checking entries in their areas of expertise. Genetics graduate students and fellows are employed periodically to review entries and note any obvious factual errors. OMIM periodically invites experts on a given disorder to review and reorganize entries. Only the on-site editorial assistants have privileges to modify the database. This is done to assure, as much as possible, that only people trained in the OMIM authoring software can make direct changes. any comments or supporting material are forwarded to a science writer for authoring. OMIM science writers are typically PhDs or MDs with training in genetics. They read the articles and...

Types of Questions

Open questions are designed to facilitate verbal output. By definition, open questions require more than a single-word response they cannot be answered with a simple yes or no. Ordinarily, open questions begin with the word How or What. Writers sometimes classify questions that begin with Where, When, Why, and or Who as open questions, but such questions are really only partially open because they don't facilitate talk nearly as well as How and What questions (Cormier & Nurius, 2003 Hutchins & Cole, 1997). The following hypothetical dialogue uses questions sometimes classified as open


Edinburgh, with its free-thinking atmosphere, was a hotbed of activity in geology, the study of the earth, and biology, the study of life. Physicians, writers, philosophers, and naturalists from all over Great Britain, Europe, and even the United States gathered in Edinburgh. To the end of his life Charles Darwin remembered seeing the American naturalist John James Audubon, dressed in the rough clothes of a backwoodsman, with his black hair streaming over his collar, demonstrating the proper way to mount a stuffed bird. All in all, Edinburgh was a heady, stimulating place for a young man beginning to explore the world of ideas and science.

Persia And Arabia

The writer Ebn-Beitar wrote about cannabis in the early thirteenth century. He described the low esteem with which cannabis users were viewed Hasan about 1260 described how Haider, leader of a holy order of fakirs, happened to eat a sample of the hemp plant whilst out walking because he was hungry. He returned to his brethren with an air of joy andgayety quite contrary to what we were accustomed to see and he subsequently encouraged all of his followers to take little nourishment but chiefly to eat of this herb. (Walton, 1938a). Another Arabic writer in 1394 described the widespread use of cannabis in the Timbaliere region


The relationship between depression and suicidal behavior is well documented (Cop-pen, 1994 Roy, 1989). Some experts believe that depression before suicide is probably universal (C. Silverman, 1968). Support for this belief includes a study by Westefeld and Furr (1987) wherein every college student in their survey sample who had attempted suicide reported experiencing at least some depressive symptoms. This close association has led some writers and researchers to label depression a lethal disease (Coppen, 1994).

Truth And Beauty

All the esthetic experience of humankind reinforces this point of view. The power of organic shapes in art, esthetics, and all forms of sensual experience is very great and this power has influenced writers, artists, and poets. Such is the power of these shapes to command the human imagination that it is impossible to credit unless their formula is indeed written into our very cells. The organic,


Cloning Dolly

In the public imagination, Dolly became a breakthrough in the struggle against perishability, and many pondered the possibility of extending life through facsimiles. Some simply hoped that cloning technology would make it possible to recreate loved ones from preserved tissue (in the mode of Creator, starring Peter O'Toole) from recently deceased children or favorite pets, but, inevitably, self-love conquered, and the idea of perpetuating oneself became a preoccupation of wistful dreamers. Richard Dawkins, the evolutionist and popular science writer, stated his own preference to recreate himself through cloning and challenged the rest of us

Focus On B F Skinner

Skinner (1904-1990) was the intellectual force behind behavior analysis. He was born Burrhus Frederic Skinner on March 20,1904, in Susquehanna, Pennsylvania. When he was a boy, Skinner spent much ofhis time exploring the countryside with his younger brother. He had a passion for English literature and mechanical inventions. His hobbies included writing stories and designing perpetual-motion machines. He wanted to be a novelist and went to Hamilton College in Clinton, New York, where he graduated with a degree in English. After graduating from college in 1926, Skinner reported that he was not a great writer because


Even more subtly, professionalization of scientific articles, including those for conservation biology and tiger beetle studies, is reflected in its evolving language, writing styles, and grammar. Linguistic analysis of journals and scientific articles shows consistent changes that indicate levels of expertise and establish levels of authority, further separating professionals from amateurs. Some examples of changing words include adverbs that show degrees of reliability, such as undoubtedly'' and possibly, induction, such as must and evidently,'' identification of hearsay evidence, such as it seems'' and ''apparently,'' reservations of deduction, such as ''presumably'' and ''could,'' and hedges, such as ''approximately'' (Chafe 1986). In addition, professional science writers use distinctive writing devices that include reduced use of personal pronouns, reliance on passive voice, a decrease in the number of simple sentences, the presence of technical terminology, an emphasis on...


(3) Even though most professional conservation biologists lack the talent or time to communicate with the public as well as Rachel Carson, Jared Diamond, Aldo Leopold, or E.O. Wilson, there are talented science writers, such as David Qua-men, Jonathan Weiner and Peter Matthiessen, who can make complex scientific writing comprehensible and attractive to a wide range of the public who have little or no science background. Cooperating with these types of writers, even though credit may be diluted, could disseminate critical information effectively to a wider audience.

General Applications

Dip pen technologies have been adapted and modified in various forms which include E-DPN or Electrochemical DPN 1, 2, 23 , electroless DPN 35 , cathodic alkyne elec-trografting 14 , DPN using diels alder reaction 28 , SP-CP or scanning probe contact printing 41 , static plowing 34 and nano-grafting 3 which has also been referred to as NPRW (nano pen reader and writer). With the exception of E-DPN and nano-grafting, which have been demonstrated for patterning of bio-molecular devices the other derivative methods have been demonstrated for only small organic, inorganic and polymer molecules and therefore are left out of the scope of the current discussion. Interested readers are advised to consult the relevant references quoted above.

Michael Yu Wang

Markup language originally developed by the publishing industry to communicate page layout information between the editor, writer and printer. The text is accompanied by embedded codes which indicate specifics of styling such as font, point size, italic, paragraph indent, line spacing, etc. Specific code systems have been developed which extend the concept to data interchange among various computer systems.

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